At Crystalline Clinic, one of the most common questions we hear from clients is: “Where can anti-wrinkle injections make the biggest difference?” It’s a great question — because while Botox and other anti-wrinkle injections can be used in multiple ways, there are a handful of areas where results are consistently powerful, natural, and confidence-boosting.
Today, we’re breaking down the top 5 anti-wrinkle injection areas we treat most frequently at our clinic. Whether you’re new to injectables or looking to expand your treatment plan, this guide will help you understand what’s possible.
Why Anti-Wrinkle Injections Work So Well
Anti-wrinkle injections are designed to temporarily relax overactive facial muscles that cause lines and wrinkles. By softening these contractions, we can smooth out existing lines and prevent new ones from forming. The result? Skin looks refreshed, smoother, and more youthful — without freezing your natural expressions.
If you’d like a detailed medical breakdown of how botulinum toxin works, you can read more on the NHS guide to Botox.
The Top 5 Anti-Wrinkle Injection Areas
1. Forehead Lines
The forehead is one of the first areas clients notice fine lines and wrinkles, especially as these dynamic lines form every time you raise your eyebrows. Over time, they can become etched in, even at rest.
Anti-wrinkle injections gently relax the muscles responsible, softening horizontal forehead lines and giving the skin a smoother, more youthful appearance. The key here is balance — at Crystalline Clinic, we never “overdo” it, ensuring you can still raise your eyebrows naturally without that frozen look.
2. Frown Lines (Glabella)
Also known as the “11 lines” between the eyebrows, frown lines can make you look tired, stressed, or even angry when you’re not. These lines form from repeated frowning, squinting, or concentrating.
Targeted injections in the glabellar area relax these muscles, softening or eliminating the lines and giving a calmer, more approachable appearance. For many of our clients, treating frown lines is a game-changer, as it dramatically refreshes the whole face.
3. Crow’s Feet (Eye Area)
The delicate skin around the eyes is especially prone to wrinkles due to frequent expressions like laughing and smiling, as well as natural ageing. Crow’s feet are the fine lines that radiate outwards from the corners of the eyes, often one of the first noticeable signs of ageing.
Anti-wrinkle injections in this area reduce muscle activity, softening these lines while still allowing your smile to shine through. The result is brighter, more youthful eyes without compromising expression.
4. Bunny Lines (Nose Wrinkles)
Bunny lines are those small, diagonal wrinkles that appear when you scrunch your nose — often visible when laughing or smiling. While they might seem minor, treating bunny lines with anti-wrinkle injections can subtly refine the face and complement other areas like the eyes and forehead.
This treatment is quick, effective, and creates a smoother, more polished look across the mid-face.
5. Jawline & Masseter Muscles
While forehead and eye areas are classics, one of the fastest-growing requests at Crystalline Clinic is jawline slimming with anti-wrinkle injections. By targeting the masseter muscles (the large chewing muscles), we can reduce teeth grinding (bruxism) and slim the lower face.
This treatment not only relieves jaw pain and headaches but also creates a softer, more contoured jawline. Many clients describe it as “two treatments in one” — functional and aesthetic.
For more insight into masseter Botox, check resources like Healthline’s explainer on Botox for jaw clenching.
Bonus Areas Worth Mentioning
While the five areas above are the most common, anti-wrinkle injections are versatile and can be used in other ways too. Popular “bonus” areas include:
- Chin dimpling (to smooth “orange peel” texture)
- Neck bands (to soften vertical platysmal bands)
- Lip flip (a subtle alternative to lip filler)
These smaller tweaks can make a huge difference when combined with the main five areas.
What to Expect During Treatment
At Crystalline Clinic, we prioritise safety, comfort, and natural results. A typical treatment process looks like this:
- Consultation – We discuss your goals, review your medical history, and map out which anti-wrinkle injection areas are best for you.
- Treatment – Using ultra-fine needles, our experienced practitioners administer tiny doses into precise points. The procedure usually takes less than 30 minutes.
- Aftercare – You can return to your day straight away, but we’ll recommend avoiding strenuous exercise, saunas, or lying flat for a few hours.
Results usually begin to show in 3–5 days, with full effects visible within two weeks.
How Long Do Results Last?
Anti-wrinkle injection results typically last 3–4 months, though some clients enjoy effects for up to six months. With regular treatments, muscles can become less active, meaning your results may last longer over time.
Consistency is key — we usually suggest scheduling maintenance treatments 3–4 times per year for optimal results.
Safety and Professional Standards
When administered by trained professionals, anti-wrinkle injections are very safe. At Crystalline Clinic, we only use licensed products and follow strict protocols to ensure every client receives care tailored to their needs.
Mild side effects like redness or slight swelling at the injection site are normal and temporary. Serious complications are extremely rare when treatments are performed by experienced clinicians.
You can find further safety information on the British Association of Dermatologists.
Why Choose Crystalline Clinic?
What sets us apart is our approach: we don’t believe in “one-size-fits-all.” Every face is unique, which is why we take the time to carefully analyse your features and recommend a personalised treatment plan. Our focus is always on enhancing your natural beauty, never masking it.
We’ve helped countless clients smooth lines, refresh their look, and restore confidence using anti-wrinkle injections — always with results that look natural, never overdone.
Final Thoughts
From forehead lines to jawline slimming, these are the top 5 anti-wrinkle injection areas that deliver the most transformative results. Whether you’re just beginning your journey with injectables or you’re ready to refine your treatment plan, our team at Crystalline Clinic is here to guide you every step of the way.
Your face tells your story — and with the right treatments, we’ll help you keep it looking as vibrant and confident as you feel.
Ready to explore your options? Book a consultation with us today and discover which anti-wrinkle injection areas are perfect for you.